MACAQUE MONKEY PROGRAM:

POSSIBLE INFECTIOUS AGENTS AND THEIR CONTROL

AGENT WORKERS AT RISK METHOD OF CONTROL COMMENTS
B Virus Macaque handlers, cage cleaners and necropsy technicians See 6 Rules to Prevent; Source: macaque monkeys shedding B virus (similar to shedding of herpes simplex virus by humans); Route: esp. through bite or scratch; infection through intact mouth or eye mucosa is possible;
Tuberculosis Macaque handlers and others who work in macaque rooms TB skin test every 6-12 months to detect converters; all new employees should have the two step test as recommended by the CDC; The monkeys are susceptible to TB. Once introduced by a human, the disease can spread quickly through the colony.
Measles Macaque handlers and others who work in macaque rooms If born after 1/1/57, then a booster (MMR) is recommended; This is just a routine immunization practice.
Hepatitis A Macaque handlers and others exposed to fecal contamination Personal protective equipment; good hand washing; offer hepatitis A vaccine; Hepatitis A vaccine is now a routine immunization for travelers to parts of the world where hepatitis A is endemic.
Hepatitis B Macaque handlers Worker training regarding sharps; offer hepatitis B vaccine; Hepatitis B is now a routine part of childhood immunizations. It is also recommended to health care workers who have exposures to patients’ blood.
Tetanus Macaque handlers Booster every 10 years or give after tetanus prone wound sustained if more than 5 years; This is just a routine immunization practice.
Bite wound infection Macaque handlers Prevention of bites by using safe handling methods; consider treatment with Augmentin after deep bites; Also consider debridement of any contused and nonviable tissue in the wound.
Rabies Macaque handlers Observe animal after bite; if becomes ill, then consider testing for rabies and beginning immunization of worker; It is unlikely that these previously quarantined primates would contract rabies.